Scientists find potential benefit of hypericin for recurrent brain tumors
Researchers have found that a synthetic version of hypericin, a compound naturally found in St. John's wort, may be a promising treatment for patients with recurrent malignant brain tumors. Their...
View ArticleCan traumatic memories be erased? Cell biology offers promise
(Medical Xpress) -- Could veterans of war, rape victims and other people who have seen horrific crimes someday have the traumatic memories that haunt them weakened in their brains? In a new study, UCLA...
View ArticleThe protein that makes us remember pain
(PhysOrg.com) -- New research by scientists in Arizona in the US has demonstrated that an enzyme makes the body remember and remain sensitive to pain after an injury has healed.
View ArticleCause and potential treatment found for cancer drug's kidney toxicity
Scientists may have a way to make the powerful cancer drug cisplatin less toxic to the kidneys and more effective against some cancers.
View ArticleIn search of the memory molecule, a key protein complex discovered
Have a tough time remembering where you put your keys, learning a new language or recalling names at a cocktail party? New research from the Lisman Laboratory at Brandeis University points to a...
View ArticleAMPK amplifies Huntington's disease
A new study describes how hyperactivation of AMP-activated protein kinase (AMPK) promotes neurodegeneration in Huntington's disease (HD). The article appears online on July 18, 2011, in The Journal of...
View ArticleEnzyme might be target for treating smoking, alcoholism at same time
An enzyme that appears to play a role in controlling the brain's response to nicotine and alcohol in mice might be a promising target for a drug that simultaneously would treat nicotine addiction and...
View ArticleThree is the magic number: A chain reaction required to prevent tumor formation
Protein p53 is known for controlling the life and death of a cell and has a key role in cancer research. P53 is known to be inactive in 50 percent of cancer patients. If researchers succeed in...
View ArticleDiabetic kidney failure follows a 'ROCK'y road
A protein kinase known as ROCK1 can exacerbate an important process called fission in the mitochondria, the power plants of cells, leading to diabetic kidney disease, said researchers from Baylor...
View ArticleNeuron memory key to taming chronic pain
For some, the pain is so great that they can't even bear to have clothes touch their skin. For others, it means that every step is a deliberate and agonizing choice. Whether the pain is caused by...
View ArticleCell energy sensor mechanism discovered: Studies linked to better...
Johns Hopkins and National Taiwan University researchers have discovered more details about how an energy sensing "thermostat" protein determines whether cells will store or use their energy reserves.
View ArticleCracking brain memory code
(Medical Xpress) -- Despite a century of research, memory encoding in the brain has remained mysterious. Neuronal synaptic connection strengths are involved, but synaptic components are short-lived...
View ArticleStudy shows how the Nanog protein promotes growth of head and neck cancer
A study led by researchers at The Ohio State University Comprehensive Cancer Center-– Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC–James) has identified a...
View ArticleResearchers find two new methods to determine ALK status
The implementation of personalized health care in cancer relies on the identification and characterization of cancer biomarkers and the availability of accurate detection systems and therapies for...
View ArticleChanges in hyaluronan metabolism—a key factor in the adaptation of...
As the outermost layer of skin, epidermis is crucial in forming a permeability barrier and protection against various environmental agents. Thus, investigating the biology of its most important cell...
View ArticleSuspicions confirmed: Brain tumors in children have a common cause
An overactive signaling pathway is a common cause in cases of pilocytic astrocytoma, the most frequent type of brain cancer in children. This was discovered by a network of scientists coordinated by...
View ArticleMutation linked to congenital urinary tract defects
Researchers at Columbia University Medical Center (CUMC) and collaborators have identified a genetic mutation that causes congenital malformations of the kidney and urinary tract, a common form of...
View ArticleAlternative target for breast cancer drugs
Scientists have identified higher levels of a receptor protein found on the surface of human breast tumour cells that may serve as a new drug target for the treatment of breast cancer. The results,...
View ArticleNew drug may protect the heart during ischemia
Research from three Yale laboratories—in the fields of immunobiology, chemistry, and cardiology—could lead to new drugs to reduce complications during cardiac surgery or heart attacks. If they pan out...
View ArticleResearchers investigate 59 tumor cell lines
In what is the biggest study of its kind to date, researchers from Technische Universität München (TUM) have identified over 10,000 different proteins in cancer cells. "Nearly all anti-tumor drugs are...
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